Yes, ISO 27001 can be integrated with an existing AS9100-based management system, but it is not plug-and-play. Integration depends on how your current QMS is structured, maturity of your processes, and the quality of your documentation and tooling. Expect some rework of procedures, controls, risk methodologies, and records to avoid conflicts, duplication, and audit gaps. In regulated aerospace environments with long-lived systems, an incremental, layered approach is usually safer than a large, all-at-once redesign.